swap a plug itself, also clean out/inspect the coil tower for that wire. Make sure all the wires are properly pushed on at both the plug and coil ends, and that there is no corrosion/water in either end.
Also, check the injector harness for that cylinder. Well, that is if you pull the plug and its dry. If its wet with fuel then you know its firing
Pull the injector wiring harness off the injector and look for corrosion, water, damage.
I think(I have never done this but it should work), being that our ignition system is wasted spark, you should be able to find out if the coil pack has one dead tower by swapping to the companion cylinder of #2 and see if the misfire follows that tower.
for a simple one cylinder misfire, its fairly easy as you have to have fuel, spark and compression. You have compresion, now you just have to check for fuel and spark.
It almost can't be the ECU, CAS, transistor pack with this because those don't do one hole only.